Abstract (deadline 28th May)
Leveraging the long-running tradition of two highly successful satellites, NetMed and NetSciReg, in 2020 we introduced NetBioMed as an integrated satellite dedicated to the importance of Network Science in Biology and Medicine. In 2021, NetBioMed will focus on the role of signal propagation, communication, and information flow in studying biological networks and understanding disease processes.
In biological systems, such as tissue networks, molecular networks, and epidemiological networks, the activity of one node impacts the subsequent state of its neighbors, triggering network cascades and leading to emergent behaviors. Both accurately modeling biological network interactions and understanding how the resulting network topology impacts system behavior, are challenging yet fundamental aspects of network science in biology and medicine.
This meeting will be targeted to network scientists whose research focuses on biomedical applications as well as biomedical scientists who are interested in learning about how network approaches can be used to study biological or disease systems at the molecular, cellular, or population level.
With the location of Networks 2021 in Washington DC, only a few miles from the US National Institutes of Health and the academic institutes that benefit from their proximity to this premier medical institute, we anticipate that there will be a high level of interest and a wide audience for biomedical networks at the conference.
Posters Session
Poster 1: Investigating resistance to IDH inhibitors in acute myeloid leukemia. Alexis Hucteau, Nina Verstraete, Feng Wang, Courtney Dinardo, Koichi Takahashi, Vera Pancaldi and Jean-Emmanuel Sarry
Poster 2: Dynamic Network Connectivity Analysis for Understanding Attention Deficit Hyperactivity Disorder. Harun Pirim, Haifeng Wang and Miaolin Fan
Poster 3: Multimodal Scrutinization of the Transcriptomic Program of Natural Killer Cells in Multiple Myeloma Patients. Rüçhan Ekren, Marie Tosolini, Virginie Baylot, Nadege Carrie-Constantin, Marie-véronique Joubert, Alexis Coulomb, Vera Pancaldi, and Ludovic Martinet
Poster 4: Quantitative study of action potential propagation in a one-dimensional strand of detrusor smooth . Shailesh Appukuttan, Rohit Manchanda and KL Brain
Organizers
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Kimberly Glass
Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School -
Vera Pancaldi
INSERM Centre de Recherches en Cancérologie de Toulouse (CRCT), France and Barcelona Supercomputing Center, Spain -
Erzsebet Regan
The College of Wooster, USA
Speakers
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9am Washington = 3pm Paris (6 hours difference)
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9:15-9:45 Michelle Girvan
Phase transitions and assortativity in models of gene regulatory networks evolved under different selection processes More information
University of Maryland, College Park, MD, USA
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9:45-10:15 Paola Paci
SWIM: a network-based approach to human diseases
National Research Council, Rome, Italy
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10:15-10:30 Florian Klimm, Enrique Toledo, Thomas Monfeuga, Fang Zhang, Charlotte Deane and Gesine Reinert
Functional module detection through integration of single-cell RNA sequencing data with protein--protein interaction networks
Contributed Talk
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10:30-10:45 Arda Halu, Edwin Silverman, Scott Weiss and Kimberly Glass
Dissecting crosstalk between signaling pathways through multilayer networks
Contributed Talk
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11:15-11:30 Marlayna Harris and Erzsébet Regan
A Boolean Model of Crosstalk Between Senescence and Epithelial to Mesenchymal Transition
Contributed Talk
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11:30-11:45 Maxime Lucas, Arthur Morris, Alex Townsend-Teague, Laurent Tichit, Bianca Habermann and Alain Barrat
Inferring cell cycle phases from a partially temporal network of protein interactions
Contributed Talk
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11:45-12:15 Paola Vera Licona
A dynamical systems and control theory approach to cell reprogramming
University of Connecticut, Connecticut, United States
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1:30-2:00 Joaquin Dopazo
Fast drug repurposing for COVID-19 using mechanistic models of signaling pathways and Real World Data validations
Hospital Virgen del Rocio, Sevilla, Spain
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2:00-2:30 Jan Bambauch
Network-based drug repurposing prediction in COVID-19 and cancer
Technical University of Munich, Germany
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2:30-2:45 Nina Verstraete, Giuseppe Jurman, Giulia Bertagnolli, Arsham Ghavasieh, Vera Pancaldi and Manlio De Domenico
CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19
Contributed Talk
Schedule EST (Washington, DC)
| Time | Slot | Description |
|---|---|---|
| 9am Washington = 3pm Paris (6 hours difference) | ||
| 9:00-9:15 | Opening Remarks | - |
| Section 1: Genomic Networks | - | |
| 9:15-9:45 | Phase transitions and assortativity in models of gene regulatory networks evolved under different selection processes Keynote | Michelle Girvan |
| 9:45-10:15 | SWIM: a network-based approach to human diseases Invited Speaker | Paola Paci |
| 10:15-10:30 | Functional module detection through integration of single-cell RNA sequencing data with protein--protein interaction networks Contributed Talk | Florian Klimm, Enrique Toledo, Thomas Monfeuga, Fang Zhang, Charlotte Deane and Gesine Reinert |
| 10:30-10:45 | Dissecting crosstalk between signaling pathways through multilayer networks Contributed Talk | Arda Halu, Edwin Silverman, Scott Weiss and Kimberly Glass |
| 10:45-11:00 | Poster Flash talks 1 | - |
| 11:00-11:15 (17:00-17:15 Paris) | Coffee break | - |
| Section 2: Modelling in Biological Systems | - | |
| 11:15-11:30 | A Boolean Model of Crosstalk Between Senescence and Epithelial to Mesenchymal Transition Contributed Talk | Marlayna Harris and Erzsébet Regan |
| 11:30-11:45 | Inferring cell cycle phases from a partially temporal network of protein interactions Contributed Talk | Maxime Lucas, Arthur Morris, Alex Townsend-Teague, Laurent Tichit, Bianca Habermann and Alain Barrat |
| 11:45-12:15 | A dynamical systems and control theory approach to cell reprogramming Invited Speaker | Paola Vera Licona |
| 12:15-1:30 (18:15-19:30 Paris) | Lunch & Poster session | - |
| Section 3: Network Medicine | - | |
| 1:30-2:00 | Fast drug repurposing for COVID-19 using mechanistic models of signaling pathways and Real World Data validations Invited speaker | Joaquin Dopazo |
| 2:00-2:30 | Network-based drug repurposing prediction in COVID-19 and cancer Invited speaker | Jan Bambauch |
| 2:30-2:45 | CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19 Contributed Talk | Nina Verstraete, Giuseppe Jurman, Giulia Bertagnolli, Arsham Ghavasieh, Vera Pancaldi and Manlio De Domenico |
| 2:45-3:00 | Poster Flash talks | - |
| Closing | - | |
| 3:00-3:15 | Closing Remarks and Discussion | - |
| 3:15-4:00 | Poster session | - |
